While in the context of substances, it ordinarily refers back to the point out of being under the impact of medicine or Alcoholic beverages.: a region where the force with the environment is greater than normal : a location of substantial barometric stress a high transferring out on the eastIf by any likelihood you spot an inappropriate remark even

unemployment/the pound has attained a whole new substantial ? die Arbeitslosenzahlen haben/das Pfund hat einen neuen Höchststand erreicht; income have achieved an all-time substantial ? die Verkaufszahlen sind so hoch wie nie zuvor; the highs and lows of my job ? die Höhen und Tiefen pl ? meiner Laufbahnreal, existent - currently being or taking